In my very first job after University, at Vega GmbH in Darmstadt, Germany, I worked on an astronaut training database for the European Astronaut Centre in Cologne. This was a browser based application that was used to train astronauts how to use various instruments that they would be using on the International Space Station. It was great fun, included lots media, videos and interactivity and was quite an advanced web application for the late 90s.
Update May 2023
I managed to get a skeletal version of the Astronaut Training Database online again. It doesn't really work as it relies on Java and CAB files which are no longer supported in most browsers. It does however give an idea of the look and feel of the tool.